The Champions League group stages reaches its halfway point this week with the Premier League leader hosting the top dogs in Italy.
Napoli's trip to Etihad Stadium to take on Manchester City in Group F promises goals aplenty, while holder Real Madrid must try and halt Tottenham's unblemished start in an intriguing clash at the Santiago Bernabeu.
Elsewhere, Liverpool and Borussia Dortmund are among the teams looking for their first European wins this season.
Here is your Opta numbers guide to Tuesday's matches.
Spartak Moscow v Sevilla
25 – Spartak has lost 25 of its previous 37 Champions League games, winning only five.
6 – Sevilla forward Wissam Ben Yedder has scored six goals in seven Champions League appearances, including four in two outings this season.
Maribor v Liverpool
0 – Maribor is winless at home in the Champions League group stages (D3 L4), having featured twice previously in 1999-00 and 2014-15.
29 – Liverpool has had 29 more shots than its opponents over its first two games (17 v Sevilla, 12 v Spartak) but is winless (D2), having conceded three goals from four shots on target faced.
Manchester City v Napoli
10 – Manchester City is on its longest run without defeat at home in the Champions League – 10 games stretching back to when Napoli's Serie A counterpart Juventus won 2-1 at the Etihad Stadium in September 2015.
12 – None of Napoli's 12 Champions League away games have ended goalless, while there has never been a 0-0 draw in any of Manchester City's 38 group games.
Feyenoord v Shakhtar Donetsk
4 – Feyenoord is unbeaten in its last four games against Ukrainian opposition (W2 D2), although it has not reached the knockout stages in four previous group stage participations and are pointless this time around.
11 – Shakhtar goalkeeper Andriy Pyatov kept out a Sergio Aguero penalty last time out and his 11 saves are the joint most in this season's competitions, alongside CSKA Moscow's Igor Akinfeev.
Monaco v Besiktas
409 – Radamel Falcao hasn't scored in his last 409 minutes of action in the Champions League, which represents the Monaco striker's longest drought in the competition.
8 – Besiktas boss Senol Gunes has drawn eight of his 14 games in the Champions League (W4 L2).
RB Leipzig v Porto
11 – Only Neymar (13) has attempted more dribbles in the Champions League this season than Porto's Yacine Brahimi.
12 – RB Leipzig has been caught offside 12 times across the two matchdays – more than any other side in the Champions League.
APOEL v Borussia Dortmund
1/46 – APOEL has won only one of its 46 games against German opposition (D7 L38). That triumph came in October 1980 when it claimed a 2-1 win at home to Dynamo Berlin in the first round of the European Cup.
4x3 – Dortmund has lost its last four Champions League games, conceding three goals on each occasion. It represents the team's longest losing streak in the competition.
Real Madrid v Tottenham
29 – Holder Real Madrid is unbeaten in the last 29 Champions League group games (W22 D7). At home it has won 21 of the last 23 (D2).
6/8 – Tottenham has scored from six of its eight shots on target in the Champions League this season. Harry Kane has been involved in each goal – assisting the first and netting the remaining five.
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