FC Porto has to do what no side has managed in the Champions League to date: overturn a five-goal deficit from the first leg. Liverpool's front three — Sadio Mane, Mohamed Salah and Roberto Firmino — had a field day at the Estadio do Dragao three weeks ago to give their team what should be an unassailable lead.

Porto is top of the Primera Liga table and has won each of its league fixtures since this record defeat to the Premier League side. But despite its excellent domestic form, Sergio Conceicao's side faces a massive challenge to even set some panic in Liverpool's ranks.

Team news

Jurgen Klopp confirmed at his pre-match press conference that Georginio Wijnaldum and Ben Woodburn will not be in contention for Tuesday's encounter due to illness. Nathaniel Clyne (back injury) is a long-term absentee. Emre Can is available for selection after serving his one-match ban. The German manager does not have fresh injury concerns from Saturday's league fixture against Newcastle United.

For Porto, left-back Alex Telles (knee injury) and midfielder Danilo Pereira (calf strain) remain injured, while Moussa Marega (hamstring) and Ricardo Pereira (thigh strain) are doubts for the second leg.

Possible formations and line-ups

Klopp has indicated that despite Liverpool holding a huge lead from the first leg, he might not rest his key personnel. Chances are Klopp might name the same or a similar line-up to the one which started against Newcastle on Saturday.

Possible Liverpool starting line-up (4-3-3): Loris Karius; Trent Alexander-Arnold, Dejan Lovren, Virgil van Dijk, Andrew Robertson; Jordan Henderson, James Milner, Alex Oxlade-Chamberlain/Adam Lallana; Mohamed Salah, Roberto Firmino, Sadio Mane

Possible Porto starting XI (4-2-3-1): Jose Sa; Maxi Pereira, Ivan Marcano, Felipe, Diogo Dalot; Hector Herrera, Sergio Oliveira; Yacine Brahimi, Otavio, Jesus Corona; Francisco dos Santos/Vincent Aboubakar


- No side in Champions League history has come from being five goals down in the first leg to win the tie
- Liverpool has lost at Anfield only once this season
- Liverpool is looking to reach its fifth Champions League quarterfinal, having last done so in 2009