Chelsea top scorer Diego Costa believes the Premier League leader can effectively end Manchester City's title hopes when the two sides meet at Stamford Bridge on Wednesday.
The alternative scenario, that fourth-placed City could win and help Tottenham Hotspur close the gap at the top to four points, does not bear thinking about for the Spain international.
The host is seven points clear of Spurs, and 11 ahead of City, which drew 2-2 at Arsenal on Sunday after twice taking the lead.
But Saturday's surprise 2-1 home defeat to lowly Crystal Palace has revived hopes elsewhere that Chelsea could be vulnerable.
That first home defeat since September was also a wake-up call for Antonio Conte's side, which has looked title certainties.
“Now is not the time to let ourselves down,” Costa, who has scored 17 league goals this season but only four since Christmas, told ESPN Brazil.
“We should keep our heads up and think ahead for the next game since it will be very important.
“This game against City will be a six-point affair since if we win...they will (effectively) be out of the title race while we keep the advantage.”
Both sides will be looking back to last year for comfort, with Chelsea winning 3-1 at the Etihad in December while City won 3-0 at Stamford Bridge last April against an off-form home side with very little to play for.
Sergio Aguero scored a hat-trick then and was also on the scoresheet against Arsenal, with manager Pep Guardiola staying hopeful.
“We know what we have to do against Chelsea. We head back to Manchester to prepare and then back down to London,” said the Spaniard, whose side have lost only one of their last six Premier League games in London.
Chelsea hope to have wing-back Victor Moses back in action after a calf injury ruled him out at the weekend.
Spurs, still without injured striker Harry Kane, can put more pressure on Chelsea when it travels to relegation-threatened Swansea City, which has never beaten it in the Premier League and is now a point above the drop zone.
Third-placed Liverpool is at home to Bournemouth while sixth-placed Arsenal, with a top four place now looking a long shot, entertain West Ham United.
Manchester United, two points clear of Arsenal in fifth, hosts Everton on Tuesday and has top scorer Zlatan Ibrahimovic available again after suspension.
At the bottom, Sunderland has a tough trip to resurgent champion Leicester City on Tuesday while last but one Middlesbrough has a basement battle against Hull City, which is one place above but four points clear, on Wednesday.
Palace travels to Southampton on Wednesday as Sam Allardyce's team seek to edge closer to safety with a fifth successive victory.
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