Edmund notched up a 7-5, 6-3, 6-1 win over Renzo Olivo book a spot in the third round.
The Canadian was ousted from the tournament by Anastasija Sevastova in the second round. Bouchard lost 6-3, 6-0.
Berdych also exited in the round of 64, losing to Karen Khachanov.
The Spaniard retired hurt in his round of 64 match against Juan Martin del Potro. He suffered a knee trouble in the third set. The players had won one set each.
Murray defeated Martin Klizan 6-, 6-2, 6-2, 7-6 in the second round.
Radwanska beat Alison Van Uytvanck 6-7(3), 6-2, 6-3 in the second round.
The duo defeated Shelby Rogers and Heather Watson 7-5, 4-6, 6-2 in the first round of women's doubles.
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