Second seed Caroline Garcia was shocked at the WTA Ladies Open Lausanne on Wednesday, downed in straight sets by Bernarda Pera.
Pera, ranked 85th in the world, proved too strong in a 6-2, 6-4 victory to set up a quarterfinal meeting against Xinyun Han.
The left-hander won the last five games of the first set and never looked back and said afterwards her second serve was key.
"You can say I'm satisfied. I played well," Pera said. "She's a tough opponent and I'm thrilled to be in the next round. I think she was struggling a lot with my second serve. I was able to break her a couple of times and that's what made the difference."
Han beat Liudmila Samsonova 7-5, 6-4, while Australian Daria Gavrilova was another big name beaten at the event, Russian Natalia Vikhlyantseva toppling the seventh seed 6-3, 6-2.
Vikhlyantseva will play third seed Alize Cornet in the last eight, the Frenchwoman coasting to a 6-1, 6-1 success against Jasmine Paolini.
Also on Wednesday, Laura Siegemund and Kristyna Pliskova won at the Bucharest Open.
Sixth seed Siegemund defeated Lara Arruabarrena 7-5, 6-3 and Pliskova did it even easier, cruising past Ysaline Bonaventure 6-0, 6-2.
Martina Di Giuseppe came from behind to topple Varvara Lepchenko 3-6, 6-1, 7-6 (7-3) and Irina-Camelia Begu beat Kaja Juvan 6-4, 6-3, while Viktoria Kuzmova defeated Jaimee Fourlis 7-5, 6-2 in the late match.