Alex Hales helped provide a strong start to England's innings, after their captain Eoin Morgan won the toss and chose to bat.
Jason Roy, the other opener, attacked as well.
Joe Root scored a half-century.
He featured in a partnership of 140 with Roy, who scored a century.
Jos Buttler unleashed his blitz, replete with unorthodox strokes, to accelerate at the death. He hit a 46-ball century to help England reach 355.
Despite a few early wickets, Pakistan were in the hunt via Mohammad Hafeez (in pic), and Babar Azam, who scored a half-century.
England chipped away by taking wickets regularly.
Shoaib Malik scored a quickfire half-century to keep Pakistan afloat.
England's spinners Adil Rashid (in pic) and Moeen Ali took six wickets between them to hurt Pakistan.
England took victory by 84 runs to clinch the four-match ODI series 3-1.
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